We all feel the ebb and flow of daily life, the daily rhythms that shape our days. The most basic daily rhythm we live by is the sleep-wake cycle, which (for most) is related to the cycle of the sun.
Researchers have identified how a fundamental biological process called protein synthesis is controlled within the body's circadian clock -- the internal mechanism that controls one's daily rhythms.
Figure 2: A single lysine of BMAL1 is acetylated. Figure 3: Acetylation of BMAL1 is essential to rescue the circadian rhythmicity in BMAL1-deficient cells. Taken together, these data demonstrate that ...