Scale-up involves increasing pump sizes, reactor volumes, and flow rates—but the process control logic and system ...

ISA106 started with the goal of developing standards, recommended practices, and technical reports on the design and implementation of procedures for automating continuous process operations. The ...

This article overviews some of the benefits and methods of state-based control as it applies to the models defined by the ISA106, Procedure Automation for Continuous Process Operations standards ...

Anything that you do well is worth doing better over time. The term "continuous improvement" describes a process practiced by quality engineers but it speaks to something that every conscientious ...

Methods to Simultaneously Reduce Bioburden and Maintain Column Integrity, Explained Continuous bioprocessing is inevitably becoming the future of biomanufacturing. To date, several steps within a ...

Key information is needed for excipients and their potential impact on continuous manufacturing processes. An essential factor to consider when developing a robust continuous manufacturing (CM) ...

Continuous process environments tend to be stable — until they’re not. When that happens, the consequences can be catastrophic. Continuous process environments tend to be stable — until they’re not.

Discussion of controllers in the continuous process industries typically centers on distributed control systems (DCSs). However, programmable logic controllers (PLCs) play as important a role in the ...