Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

Genes make up the blueprints and outline the process of building every living organism. To ensure that the right genes are activated in the right cells, and in the right amounts at the right time, ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Inducible promoters provide remarkable utility when sustained transgene expression compromises plant development or agronomic performance. In this study, four different plant heat shock protein (HSP) ...

Northwestern Medicine scientists have discovered how molecular "traffic controllers" in cells influence aging and cellular senescence—a state where cells stop dividing but remain metabolically active.

Inducible promoters provide remarkable utility when sustained transgene expression compromises plant development or agronomic ...