Spatial transcriptomics and gene expression analysis represent a transformative approach in biomedical research, integrating the spatial context of tissues with high-resolution profiling of gene ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and ...

Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these ...

Nova-ST, a new spatial transcriptomics technique, has been introduced by researchers based at Vlaams Instituut voor Biotechnologie (VIB), Katholieke Universiteit (KU) Leuven. According to the ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Strapped with an extra APP, people with Down’s syndrome are all but destined to develop Alzheimer’s dementia if they live past middle age. Compared with sporadic forms of the disease, DSAD starts ...