Cancer is often thought of as a single disease. Yet even tumors that arise in the same organ can follow very different genetic paths. A new study shows that these differences can sometimes be traced ...

KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells to multiply without restraint. Decades of research have traced this process ...

Cerebrospinal fluid circulating tumor DNA for the detection and characterization of leptomeningeal metastasis in non-small cell lung cancer. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...

Experiments from the 1940s established a key tenet of genetics—mutagenesis occurs randomly across the genome. New research, however, suggests that mutations may be less random than originally thought.