Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Over the past two decades, cell biologists and computational biologists have worked to develop lineage tracing techniques that can decode the ...

Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain, representing eight different brain regions and 36 different cell types to show clear epigenetic ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to ...

A key Alzheimer’s drug has finally revealed its secret. Researchers discovered that lecanemab works by activating the brain’s immune cells—but only through a specific part of the antibody called the ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

This article explores how multiomics integration, imaging, and bioinformatics are advancing biomarker discovery, revealing ...

Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, driven by complex and heterogeneous molecular mechanisms ...

Researchers developed a method that visualizes gene activity across an entire embryo with high spatial detail. The resulting ...

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...